With the rapid development of the global economy and scientific and technological progress, the production of fine chemicals and chemical raw materials has entered a mature period. After entering the 21st century, the development of pharmaceuticals is not solely dependent on the general level of technology can leap, more importantly, rely on new breakthroughs in science and technology.
To date, the global synthetic compounds have reached more than 10 million, fine chemicals sales of 50 billion U.S. dollars, with an annual growth rate of about 5%, in which pharmaceutical intermediates and chemical bulk drugs occupy a dominant position.
Chemical bulk drugs industry is an important foundation of the pharmaceutical industry, the world's production of bulk drugs has reached more than 2,000 kinds, the market size of nearly 10 billion U.S. dollars in 1996 to 13 billion U.S. dollars in 2000, with an annual growth rate of about 7%, and foreign pharmaceutical manufacturers need chemical bulk drugs and intermediates 60% through outsourcing or contract production.
Several major bulk drugs production regions in the world are: Western Europe, North America, Japan, China and India. Among them, Western Europe is the pure export of bulk drugs region, the current total value of bulk drugs close to 6 billion U.S. dollars, known as the world's largest bulk drugs production base, accounting for 50% of the global total, while exports account for more than 80% of its total production.
North America is the main import region of bulk drugs, the region consumes about 4 billion U.S. dollars of various bulk drugs each year, accounting for 1/3 of the world bulk drugs consumption market, environmental reasons, many of the more polluting pharmaceutical bulk drugs in the region is no longer produced, half of its bulk drugs consumption for self-production, another 50% rely on imports.
In recent years, North America are required to import hundreds of bulk drugs worth more than 2 billion U.S. dollars, and its dependence on the proportion of imports has gradually expanded the trend, the region's production accounts for only 18% of the global total.
Japan is the world's pharmaceutical industry powerhouse, its pharmaceutical bulk drugs market size between the United States and Western Europe, the annual demand for about 1.5 billion U.S. dollars, in addition to a very few varieties, the vast majority of its own production, there are predictions that, with the rising cost of labor and environmental problems, Japan will be purely imported to the raw materials change, is basically in a self-sufficient situation.
With the continuous improvement of China's production technology, pharmaceutical equipment is becoming more and more perfect, as well as joint venture pharmaceutical companies to seize the Chinese market for bulk drugs, the world's bulk drugs production center has gradually shifted to Asia. China and India's bulk drugs production is rising rbulk drugsdly. India's production and import and export volume is comparable to China, is China's bulk drugs in the international market's largest competitors.