Aolisenchem provides chemical intermediates 3-Bromo-2-fluorobenzoic acid CAS#161957-56-8, which is used as a reagent to synthesize Dabrafenib, an inhibitor of BRAF kinase that is used to treat BRAF V600-mutation positive carcinoma. BRAF is a gene that mediates cell growth and is activated by mutations caused by cancer. It is also used as a reagent to prepare Alkynlphenoxyacetic acid receptor agonists, compounds that can be potentially used for the treatment of allergic inflammatory diseases (such as allergic rhinitis).
Appearance: white to light yellow solid
Purity: 98%
Melting Point: 168 °C
Boiling point: 298.2°C at 760 mmHg
Water (KF): 0.5%
CAS Number | 161957-56-8 |
Molecular Formula | C7H4BrFO2 |
Molecular Weight | 219.01 |
MDL Number | MFCD00665763 |
Signal word: Warning
Hazard statement(s):
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
General advice:
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled:
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
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